Inhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells. [electronic resource]
Producer: 20151007Description: e0116575 p. digitalISSN:- 1932-6203
- Calcium -- metabolism
- Cell Line
- GTP-Binding Protein beta Subunits -- antagonists & inhibitors
- GTP-Binding Protein gamma Subunits -- antagonists & inhibitors
- Gene Expression Regulation -- drug effects
- Gene Silencing
- Humans
- Interleukin-2 -- genetics
- NFATC Transcription Factors -- metabolism
- Promoter Regions, Genetic
- Protein Transport
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Receptors, Antigen, T-Cell -- metabolism
- Signal Transduction -- drug effects
- T-Lymphocytes, Helper-Inducer -- drug effects
- Time Factors
- Transcription, Genetic
- Xanthenes -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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