Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation. [electronic resource]
Producer: 20150804Description: 421-9 p. digitalISSN:- 1349-7006
- Animals
- Apoptosis -- drug effects
- Binding Sites -- drug effects
- Burkitt Lymphoma -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin D1 -- genetics
- Cyclin-Dependent Kinase 4 -- genetics
- DNA-Binding Proteins
- E-Box Elements -- drug effects
- Eukaryotic Initiation Factor-4G -- genetics
- Humans
- Imidazoles -- chemistry
- Mice
- Mice, SCID
- Nylons -- chemical synthesis
- Promoter Regions, Genetic
- Protein Binding -- drug effects
- Proto-Oncogene Proteins c-myc -- antagonists & inhibitors
- Pyrroles -- chemistry
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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