Mutant PIK3CA controls DUSP1-dependent ERK 1/2 activity to confer response to AKT target therapy. [electronic resource]
Producer: 20150126Description: 2103-13 p. digitalISSN:- 1532-1827
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Chickens
- Chorioallantoic Membrane
- Class I Phosphatidylinositol 3-Kinases
- Dual Specificity Phosphatase 1 -- physiology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Molecular Targeted Therapy
- Mutation
- Phosphatidylinositol 3-Kinases -- genetics
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Urinary Bladder Neoplasms -- drug therapy
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Publication Type: Journal Article
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