Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. [electronic resource]
Producer: 20150430Description: 14530-5 p. digitalISSN:- 1091-6490
- Animals
- Arachidonate 5-Lipoxygenase -- metabolism
- Arachidonic Acid -- pharmacology
- Calcium -- metabolism
- Calcium-Calmodulin-Dependent Protein Kinase Type 2 -- genetics
- Cell Nucleus -- drug effects
- Cells, Cultured
- Cytoplasm -- drug effects
- Docosahexaenoic Acids -- pharmacology
- Dose-Response Relationship, Drug
- Female
- Immunoblotting
- Intracellular Signaling Peptides and Proteins -- metabolism
- Leukotriene B4 -- biosynthesis
- Macrophages -- cytology
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Microscopy, Confocal
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Receptors, Formyl Peptide -- metabolism
- Serine -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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