Pharmacokinetics, antitumor and cardioprotective effects of liposome-encapsulated phenylaminoethyl selenide in human prostate cancer rodent models. [electronic resource]
Producer: 20151103Description: 852-62 p. digitalISSN:- 1573-904X
- Animals
- Antineoplastic Agents -- administration & dosage
- Antioxidants -- administration & dosage
- Area Under Curve
- Cardiomegaly -- chemically induced
- Cell Line, Tumor
- Chemistry, Pharmaceutical
- Chromatography, Liquid
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Doxorubicin
- Ethylamines -- administration & dosage
- Gene Expression Regulation -- drug effects
- Half-Life
- Humans
- Injections, Intravenous
- Liposomes
- Male
- Mass Spectrometry
- Metabolic Clearance Rate
- Mice, Nude
- Myocytes, Cardiac -- drug effects
- Organoselenium Compounds -- administration & dosage
- Oxidative Stress -- drug effects
- Prostatic Neoplasms -- drug therapy
- Rats, Inbred F344
- Reactive Oxygen Species -- metabolism
- Technology, Pharmaceutical -- methods
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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