Vitamin C protects against cisplatin-induced nephrotoxicity and damage without reducing its effectiveness in C57BL/6 mice xenografted with Lewis lung carcinoma. [electronic resource]
Producer: 20150630Description: 1085-91 p. digitalISSN:- 1532-7914
- Animals
- Antineoplastic Agents -- administration & dosage
- Ascorbic Acid -- pharmacology
- Blood Urea Nitrogen
- Carcinoma, Lewis Lung -- drug therapy
- Cell Line, Tumor
- Cisplatin -- administration & dosage
- Creatinine -- blood
- Glutathione -- metabolism
- Kidney -- drug effects
- Kidney Diseases -- chemically induced
- Lipid Peroxidation -- drug effects
- Liver -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Oxidative Stress -- drug effects
- Protein Carbonylation -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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