A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling. [electronic resource]
Producer: 20141210Description: 146 p. digitalISSN:- 1476-4598
- Androgens -- metabolism
- Cell Line, Tumor
- Feedback, Physiological
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Microtubule Proteins -- biosynthesis
- Neoplasms, Hormone-Dependent -- genetics
- Nuclear Proteins -- biosynthesis
- Phosphatidylinositol 3-Kinases -- metabolism
- Promoter Regions, Genetic
- Prostatic Neoplasms, Castration-Resistant -- genetics
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptors, Androgen -- metabolism
- Signal Transduction
- Transcription Factors -- biosynthesis
- Ubiquitin-Protein Ligases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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