Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. [electronic resource]
Producer: 20141006Description: e83145 p. digitalISSN:- 1932-6203
- Animals
- Biological Transport
- Cell Line
- Cholesterol -- analogs & derivatives
- Cholesterol, LDL -- metabolism
- Gene Expression Regulation
- Humans
- Inflammation -- genetics
- Intracellular Signaling Peptides and Proteins -- deficiency
- JNK Mitogen-Activated Protein Kinases -- genetics
- Lipoproteins, LDL -- chemistry
- Lymphocyte Antigen 96 -- genetics
- MAP Kinase Kinase 4 -- genetics
- Macrophages -- drug effects
- Mice
- Mice, Knockout
- Mitogen-Activated Protein Kinase 1 -- genetics
- Mitogen-Activated Protein Kinase 3 -- genetics
- Oxidation-Reduction
- Plaque, Atherosclerotic -- genetics
- Primary Cell Culture
- Protein Multimerization
- Protein-Tyrosine Kinases -- deficiency
- Signal Transduction
- Syk Kinase
- Toll-Like Receptor 4 -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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