Adipocyte-derived factors impair insulin signaling in differentiated human vascular smooth muscle cells via the upregulation of miR-143. [electronic resource]
Producer: 20140416Description: 275-83 p. digitalISSN:- 0006-3002
- Adipocytes -- cytology
- Adult
- Blotting, Western
- Cell Differentiation -- drug effects
- Cells, Cultured
- Culture Media, Conditioned -- metabolism
- Female
- HEK293 Cells
- Humans
- Insulin -- metabolism
- MicroRNAs -- genetics
- Middle Aged
- Muscle, Smooth, Vascular -- cytology
- Myocytes, Smooth Muscle -- cytology
- Phosphorylation -- drug effects
- RNA Interference
- Receptors, Steroid -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Smad2 Protein -- genetics
- Up-Regulation -- drug effects
- p38 Mitogen-Activated Protein Kinases -- genetics
- Oxysterol Binding Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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