Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression. [electronic resource]
Producer: 20140227Description: 1655-60 p. digitalISSN:- 1546-170X
- Adult
- Aged
- Animals
- Female
- Gene Expression Regulation
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Hypertension -- chemically induced
- Male
- Mice
- Mice, Transgenic
- Middle Aged
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic -- genetics
- Renal Insufficiency, Chronic -- genetics
- Sodium, Dietary -- adverse effects
- Up-Regulation
- Uromodulin -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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