Saturated free fatty acid sodium palmitate-induced lipoapoptosis by targeting glycogen synthase kinase-3β activation in human liver cells. [electronic resource]
Producer: 20140410Description: 346-57 p. digitalISSN:- 1573-2568
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Shape -- drug effects
- Endoplasmic Reticulum Stress -- drug effects
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Fatty Liver -- chemically induced
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Hep G2 Cells
- Hepatocytes -- drug effects
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Liver -- drug effects
- Non-alcoholic Fatty Liver Disease
- Palmitic Acid -- toxicity
- Phosphorylation
- RNA Interference
- Signal Transduction -- drug effects
- Time Factors
- Transfection
- Unfolded Protein Response -- drug effects
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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