Fenofibrate attenuated glucose-induced mesangial cells proliferation and extracellular matrix synthesis via PI3K/AKT and ERK1/2. [electronic resource]
Producer: 20140624Description: e76836 p. digitalISSN:- 1932-6203
- Animals
- Cell Cycle Checkpoints -- drug effects
- Cell Line
- Cell Proliferation -- drug effects
- Collagen Type IV -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Extracellular Matrix -- drug effects
- Fenofibrate -- pharmacology
- Glucose -- pharmacology
- MAP Kinase Signaling System -- drug effects
- Mesangial Cells -- cytology
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- PPAR alpha -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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