Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape. [electronic resource]
Producer: 20140714Description: e75490 p. digitalISSN:- 1932-6203
- Animals
- Bacterial Toxins -- metabolism
- Cell Line
- Cholesterol -- metabolism
- Heat-Shock Proteins -- metabolism
- Hemolysin Proteins -- metabolism
- Interleukin-12 Subunit p40 -- metabolism
- Listeria monocytogenes -- drug effects
- Listeriosis -- drug therapy
- Liver -- drug effects
- Macrophages -- metabolism
- Mice
- Mice, Inbred C57BL
- Phagocytosis -- drug effects
- Phagosomes -- drug effects
- Simvastatin -- pharmacology
- Spleen -- drug effects
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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