A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. [electronic resource]
Producer: 20140729Description: 1364-77 p. digitalISSN:- 2159-8290
- Animals
- Antidepressive Agents, Tricyclic -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Computational Biology
- Drug Repositioning
- Humans
- Lung Neoplasms -- drug therapy
- Mice
- Neuroendocrine Tumors -- drug therapy
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Small Cell Lung Carcinoma -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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