A binuclear complex constituted by diethyldithiocarbamate and copper(I) functions as a proteasome activity inhibitor in pancreatic cancer cultures and xenografts. [electronic resource]
Producer: 20140210Description: 477-83 p. digitalISSN:- 1096-0333
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinogenesis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Copper -- pharmacology
- Disease Models, Animal
- Disulfiram -- pharmacology
- Ditiocarb -- pharmacology
- Female
- Humans
- In Situ Nick-End Labeling
- Mice
- Mice, Nude
- NF-kappa B -- antagonists & inhibitors
- Pancreatic Neoplasms -- drug therapy
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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