An acidic microenvironment increases NK cell killing of Cryptococcus neoformans and Cryptococcus gattii by enhancing perforin degranulation. [electronic resource]
Producer: 20140218Description: e1003439 p. digitalISSN:- 1553-7374
- Cell Adhesion
- Cell Degranulation
- Cell Line
- Cells, Cultured
- Cellular Microenvironment
- Cerebral Cortex -- immunology
- Cryptococcosis -- immunology
- Cryptococcus gattii -- immunology
- Cryptococcus neoformans -- immunology
- Cytotoxicity, Immunologic
- Fungal Proteins -- genetics
- Humans
- Hydrogen-Ion Concentration
- Killer Cells, Natural -- immunology
- Lung -- immunology
- MAP Kinase Signaling System
- Perforin -- metabolism
- Phosphorylation
- Protein Processing, Post-Translational
- Up-Regulation
- Virus Replication
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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