Selective inhibition of tumor necrosis factor-α converting enzyme attenuates liver toxicity in a murine model of concanavalin A induced auto-immune hepatitis. [electronic resource]
Producer: 20140422Description: 229-36 p. digitalISSN:- 1878-1705
- ADAM Proteins -- antagonists & inhibitors
- ADAM17 Protein
- Alanine Transaminase -- metabolism
- Animals
- Aspartate Aminotransferases -- metabolism
- Cells, Cultured
- Concanavalin A -- immunology
- Cytokines -- metabolism
- Disease Models, Animal
- Down-Regulation
- Fibrosis
- Hepatitis, Autoimmune -- drug therapy
- Hepatocytes -- drug effects
- Inflammation Mediators -- metabolism
- Liver -- drug effects
- Mice
- Mice, Inbred BALB C
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases -- genetics
- Quinolines -- administration & dosage
- Tissue Inhibitor of Metalloproteinase-1 -- genetics
- Transcriptional Activation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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