Structure-guided design of a selective BCL-X(L) inhibitor. [electronic resource]
Producer: 20130715Description: 390-7 p. digitalISSN:- 1552-4469
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Benzothiazoles -- chemistry
- Cell Line, Tumor
- Crystallography, X-Ray
- Drug Design
- Drug Screening Assays, Antitumor
- Humans
- Hydrazones -- chemistry
- Kinetics
- Mice
- Models, Chemical
- Myeloid Cell Leukemia Sequence 1 Protein
- Protein Binding
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- bcl-X Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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