A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation. [electronic resource]
Producer: 20130624Description: 1488-507 p. digitalISSN:- 1460-2156
- Aminopeptidases -- deficiency
- Animals
- Animals, Genetically Modified
- Cell Proliferation
- Dipeptidyl-Peptidases and Tripeptidyl-Peptidases -- deficiency
- Disease Models, Animal
- Disease Progression
- Growth Inhibitors -- deficiency
- Humans
- Motor Activity -- physiology
- Neurodegenerative Diseases -- enzymology
- Neuronal Ceroid-Lipofuscinoses -- enzymology
- Serine Proteases -- deficiency
- Tripeptidyl-Peptidase 1
- Zebrafish
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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