FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. [electronic resource]
Producer: 20131022Description: e61017 p. digitalISSN:- 1932-6203
- Apoptosis -- genetics
- Caspase 3 -- metabolism
- Caveolin 1 -- genetics
- Cell Line
- Collagen Type I -- chemistry
- Fibroblasts -- metabolism
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- deficiency
- Gene Expression Regulation
- Humans
- Idiopathic Pulmonary Fibrosis -- genetics
- Lung -- metabolism
- PTEN Phosphohydrolase -- metabolism
- Phenotype
- Protein Multimerization
- Proto-Oncogene Proteins c-akt -- metabolism
- fas Receptor -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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