Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy. [electronic resource]
Producer: 20130926Description: 729-39 p. digitalISSN:- 1536-4844
- Adult
- Antibodies, Monoclonal -- adverse effects
- Antigens, CD -- genetics
- Antigens, Differentiation, Myelomonocytic -- genetics
- Apoptosis -- drug effects
- Case-Control Studies
- Cell Differentiation -- drug effects
- Cell Proliferation -- drug effects
- Colitis, Ulcerative -- drug therapy
- Crohn Disease -- drug therapy
- Down-Regulation
- Endoscopy
- Female
- Gastrointestinal Agents -- adverse effects
- Granulocyte-Macrophage Colony-Stimulating Factor -- genetics
- Humans
- Infliximab
- Interleukin-17 -- genetics
- Intestinal Mucosa -- drug effects
- Macrophages -- drug effects
- Male
- Microscopy, Fluorescence
- Middle Aged
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Wound Healing
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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