Synthesis of N(4)-(substituted phenyl)-N(4)-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells. [electronic resource]
Producer: 20130816Description: 891-902 p. digitalISSN:- 1464-3391
- Aniline Compounds -- chemistry
- Binding Sites
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colchicine -- chemistry
- Cyclization
- Cyclohexanones -- chemistry
- Diamines -- chemical synthesis
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor
- Humans
- Indoles -- chemistry
- Microtubules -- chemistry
- Molecular Docking Simulation
- Oxidation-Reduction
- Protein Binding
- Protein Structure, Tertiary
- Pyrimidines -- chemistry
- Tubulin Modulators -- chemical synthesis
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.