Novel bis-C,N-cyclometalated iridium(III) thiosemicarbazide antitumor complexes: interactions with human serum albumin and DNA, and inhibition of cathepsin B. [electronic resource]
Producer: 20130812Description: 974-82 p. digitalISSN:- 1520-510X
- Antineoplastic Agents -- chemical synthesis
- Binding, Competitive
- Breast Neoplasms -- drug therapy
- Cathepsin B -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Survival -- drug effects
- Crystallography, X-Ray
- DNA -- chemistry
- Electrophoresis, Gel, Two-Dimensional
- Enzyme Activation -- drug effects
- Female
- Humans
- Inhibitory Concentration 50
- Iridium -- chemistry
- Organometallic Compounds -- chemical synthesis
- Ovarian Neoplasms -- drug therapy
- Semicarbazides -- chemical synthesis
- Serum Albumin -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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