Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia. [electronic resource]
Producer: 20130822Description: 293-306 p. digitalISSN:- 1538-7836
- Animals
- Cytokines -- metabolism
- Disease Models, Animal
- Factor VIII -- genetics
- Gene Expression Profiling
- Gene Expression Regulation
- Genotype
- Hemarthrosis -- blood
- Hemophilia A -- blood
- Inflammation -- blood
- Inflammation Mediators -- metabolism
- Knee Joint -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- MicroRNAs -- metabolism
- NF-kappa B -- genetics
- Phenotype
- Reproducibility of Results
- Signal Transduction
- Synovial Fluid -- immunology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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