Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling. [electronic resource]
Producer: 20131107Description: 1359-71 p. digitalISSN:- 1745-7254
- Administration, Intravenous
- Administration, Oral
- Adrenergic beta-1 Receptor Antagonists -- administration & dosage
- Adult
- Area Under Curve
- Bisoprolol -- administration & dosage
- Computer Simulation
- Dose-Response Relationship, Drug
- Female
- Humans
- Male
- Middle Aged
- Models, Biological
- Monte Carlo Method
- Renal Insufficiency -- physiopathology
- Tissue Distribution
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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