Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II). [electronic resource]
Producer: 20121219Description: 3596-603 p. digitalISSN:- 1527-7755
- Administration, Oral
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Brazil
- Capecitabine
- Colorectal Neoplasms -- drug therapy
- Deoxycytidine -- analogs & derivatives
- Disease-Free Survival
- Dose-Response Relationship, Drug
- Double-Blind Method
- Drug Administration Schedule
- Female
- Fluorouracil -- analogs & derivatives
- Humans
- Infusions, Intravenous
- Kaplan-Meier Estimate
- Leucovorin -- therapeutic use
- Male
- Middle Aged
- Neoplasm Invasiveness -- pathology
- Neoplasm Metastasis
- Neoplasm Staging
- Organoplatinum Compounds -- therapeutic use
- Prognosis
- Proportional Hazards Models
- Pyridines -- therapeutic use
- Quinazolines -- therapeutic use
- Survival Analysis
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Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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