Leptin-induced cardiomyocyte hypertrophy reveals both calcium-dependent and calcium-independent/RhoA-dependent calcineurin activation and NFAT nuclear translocation. [electronic resource]
Producer: 20130307Description: 2283-90 p. digitalISSN:- 1873-3913
- Animals
- Calcineurin -- metabolism
- Calcineurin Inhibitors
- Calcium -- metabolism
- Cardiomegaly -- metabolism
- Cell Nucleus -- metabolism
- Cells, Cultured
- Leptin -- pharmacology
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Myocytes, Cardiac -- drug effects
- NFATC Transcription Factors -- metabolism
- Phosphorylation -- drug effects
- Rats
- Signal Transduction
- Sodium-Potassium-Exchanging ATPase -- metabolism
- Tacrolimus -- pharmacology
- Thiourea -- analogs & derivatives
- Translocation, Genetic -- drug effects
- p38 Mitogen-Activated Protein Kinases -- metabolism
- rhoA GTP-Binding Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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