New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer's disease. [electronic resource]
Producer: 20121214Description: 84 p. digitalISSN:- 1471-2202
- Alzheimer Disease -- complications
- Amyloid Precursor Protein Secretases -- cerebrospinal fluid
- Amyloid beta-Peptides -- metabolism
- Animals
- Cells, Cultured
- Cerebral Cortex -- cytology
- Cognition Disorders -- etiology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Embryo, Mammalian
- Enzyme Inhibitors -- pharmacology
- Humans
- Linear Models
- Mice
- Mice, Transgenic
- Neuroblastoma -- metabolism
- Neurons -- metabolism
- Peptide Fragments -- metabolism
- Presenilin-1 -- genetics
- Spinal Puncture
- Time Factors
- tau Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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