The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation. [electronic resource]
Producer: 20130702Description: 296-306 p. digitalISSN:- 1557-8534
- Benzamides -- pharmacology
- Blastocyst Inner Cell Mass -- cytology
- Cell Count
- Cell Culture Techniques
- Cell Lineage
- Diphenylamine -- analogs & derivatives
- Embryo Culture Techniques
- Embryo Implantation -- drug effects
- Embryonic Stem Cells -- cytology
- GATA6 Transcription Factor -- genetics
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Homeodomain Proteins -- genetics
- Humans
- Immunohistochemistry
- MAP Kinase Signaling System
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Nanog Homeobox Protein
- Octamer Transcription Factor-3 -- genetics
- Pyridines -- pharmacology
- Pyrimidines -- pharmacology
- Signal Transduction
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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