Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation. [electronic resource]
Producer: 20130417Description: 1950-61 p. digitalISSN:- 1476-5403
- Apoptosis -- drug effects
- Cyclin-Dependent Kinase 9 -- antagonists & inhibitors
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Dichlororibofuranosylbenzimidazole -- pharmacology
- HL-60 Cells
- Hep G2 Cells
- Humans
- Inflammation -- metabolism
- Neutrophils -- drug effects
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Purines -- pharmacology
- RNA Polymerase II -- metabolism
- Roscovitine
- Transcription, Genetic
- Cyclin-Dependent Kinase-Activating Kinase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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