Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus. [electronic resource]
Producer: 20130422Description: 739-47 p. digitalISSN:- 1440-1797
- Animals
- Embryo, Mammalian -- drug effects
- Feasibility Studies
- Female
- Gene Expression Regulation, Developmental
- Genetic Predisposition to Disease
- Gestational Age
- Homozygote
- Kidney -- drug effects
- Male
- Mice
- Mice, Inbred C3H
- Mice, Knockout
- PAX2 Transcription Factor -- metabolism
- Phenotype
- Polycystic Kidney, Autosomal Dominant -- embryology
- Protein Kinase Inhibitors -- pharmacology
- Sequence Deletion
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- TRPP Cation Channels -- deficiency
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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