Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. [electronic resource]
Producer: 20120418Description: 100-3 p. digitalISSN:- 1476-4687
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cetuximab
- Colorectal Neoplasms -- drug therapy
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Enzyme Activation -- drug effects
- ErbB Receptors -- agonists
- Erlotinib Hydrochloride
- Feedback, Physiological -- drug effects
- Female
- Gefitinib
- HEK293 Cells
- Humans
- Indoles -- pharmacology
- Melanoma -- drug therapy
- Mice
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Quinazolines -- pharmacology
- RNA Interference
- Sulfonamides -- pharmacology
- Vemurafenib
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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