Antibody breadth and protective efficacy are increased by vaccination with computationally optimized hemagglutinin but not with polyvalent hemagglutinin-based H5N1 virus-like particle vaccines. [electronic resource]
Producer: 20120627Description: 128-39 p. digitalISSN:- 1556-679X
- Animals
- Antibodies, Viral -- blood
- Antibody Formation -- immunology
- Female
- Ferrets
- Hemagglutinin Glycoproteins, Influenza Virus -- immunology
- Influenza A Virus, H5N1 Subtype -- immunology
- Influenza Vaccines -- immunology
- Lung -- pathology
- Mice
- Mice, Inbred BALB C
- Orthomyxoviridae Infections -- immunology
- Vaccination
- Vaccines, Virus-Like Particle -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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