Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3. [electronic resource]
Producer: 20120118Description: 3922-32 p. digitalISSN:- 2219-2840
- Animals
- Antineoplastic Agents -- pharmacology
- Benzenesulfonates -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Enzyme Inhibitors -- metabolism
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Janus Kinase 2 -- metabolism
- Liver Neoplasms -- drug therapy
- Male
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Neoplasm Metastasis
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyridines -- pharmacology
- Rats
- STAT3 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Sorafenib
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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