Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice. [electronic resource]
Producer: 20121019Description: 766-77 p. digitalISSN:- 1090-2139
- Aging -- physiology
- Animals
- Cell Separation
- Cells, Cultured
- Flow Cytometry
- Inflammation -- metabolism
- Interleukin-10 Receptor alpha Subunit -- biosynthesis
- Interleukin-4 -- pharmacology
- Interleukin-4 Receptor alpha Subunit -- biosynthesis
- Lipopolysaccharides -- pharmacology
- Macrophage Activation -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- Microglia -- drug effects
- RNA -- biosynthesis
- Real-Time Polymerase Chain Reaction
- Receptors, Cell Surface -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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