Optimized quantities of GDNF overexpressed by engineered astrocytes are critical for protection of neuroblastoma cells against 6-OHDA toxicity. [electronic resource]
Producer: 20130225Description: 654-65 p. digitalISSN:- 1559-1166
- Animals
- Apoptosis -- drug effects
- Astrocytes -- pathology
- Astrocytoma -- genetics
- Cell Death -- drug effects
- Cell Line, Tumor
- Cytoprotection -- genetics
- Feasibility Studies
- Genetic Engineering -- methods
- Genetic Vectors -- genetics
- Glial Cell Line-Derived Neurotrophic Factor -- genetics
- HEK293 Cells
- Humans
- Mice
- Mice, Inbred C57BL
- Neuroblastoma -- genetics
- Oxidopamine -- toxicity
- Parkinson Disease -- metabolism
- Sympatholytics -- toxicity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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