Silicon analogues of the nonpeptidic GnRH antagonist AG-045572: syntheses, crystal structure analyses, and pharmacological characterization. [electronic resource]
Producer: 20120413Description: 2070-80 p. digitalISSN:- 1860-7187
- Animals
- Crystallography, X-Ray
- Drug Evaluation, Preclinical
- Furans -- chemistry
- Gonadotropin-Releasing Hormone -- antagonists & inhibitors
- Hormone Antagonists -- chemistry
- Humans
- Luteinizing Hormone -- antagonists & inhibitors
- Magnetic Resonance Spectroscopy
- Male
- Molecular Structure
- Orchiectomy
- Rats, Wistar
- Receptors, LHRH -- genetics
- Silicon -- chemistry
- Structure-Activity Relationship
- Tetrahydronaphthalenes -- chemistry
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Publication Type: Journal Article
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