Modulation of in vitro monocyte cytokine responses to Leishmania donovani. Interferon-gamma prevents parasite-induced inhibition of interleukin 1 production and primes monocytes to respond to Leishmania by producing both tumor necrosis factor-alpha and interleukin 1. [electronic resource]
Producer: 19900711Description: 1914-24 p. digitalISSN:- 0021-9738
- Animals
- Blotting, Northern
- Cells, Cultured
- Gene Expression -- drug effects
- Humans
- Immunity, Cellular
- In Vitro Techniques
- Interferon-gamma -- pharmacology
- Interleukin-1 -- biosynthesis
- Leishmania donovani -- immunology
- Leishmaniasis, Visceral -- immunology
- Lipopolysaccharides -- pharmacology
- Monocytes -- immunology
- RNA, Messenger -- genetics
- Staphylococcus aureus -- immunology
- Tumor Necrosis Factor-alpha -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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