Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. [electronic resource]
Producer: 20120511Description: 2298-308 p. digitalISSN:- 1538-8514
- Angiogenesis Inhibitors -- pharmacology
- Anilides -- pharmacology
- Animals
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Drug Evaluation, Preclinical
- Female
- Humans
- Mice
- Mice, Nude
- Models, Biological
- Neoplasm Metastasis -- prevention & control
- Neoplasms -- drug therapy
- Neovascularization, Pathologic -- drug therapy
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- Pyridines -- pharmacology
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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