Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis. [electronic resource]
Producer: 20120229Description: 2951-63 p. digitalISSN:- 1477-9137
- 14-3-3 Proteins -- deficiency
- Apoptosis -- genetics
- Ataxia Telangiectasia Mutated Proteins
- Biomarkers, Tumor -- deficiency
- Caspases -- metabolism
- Cell Cycle Proteins -- genetics
- Chromatids -- drug effects
- Chromosome Aberrations -- chemically induced
- Chromosome Breakage
- DNA Damage
- DNA-Binding Proteins -- genetics
- Doxorubicin -- pharmacology
- Exonucleases -- deficiency
- Exoribonucleases
- G1 Phase -- genetics
- Gene Knockout Techniques
- Genomic Instability
- HCT116 Cells
- Histones -- genetics
- Humans
- Mitosis -- genetics
- Phosphorylation
- Protein Serine-Threonine Kinases -- genetics
- S Phase -- genetics
- Signal Transduction
- Tumor Suppressor Protein p53 -- genetics
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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