The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation. [electronic resource]
Producer: 20120524Description: 305-20 p. digitalISSN:- 1748-7838
- Amino Acid Motifs
- Animals
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Checkpoints
- Cell Cycle Proteins -- metabolism
- Cells, Cultured
- Checkpoint Kinase 1
- Chromosomal Instability
- DNA Breaks, Double-Stranded
- DNA Repair -- physiology
- DNA Repair Enzymes -- chemistry
- DNA-Binding Proteins -- chemistry
- Enzyme Activation
- Gamma Rays
- Gene Knock-In Techniques
- MRE11 Homologue Protein
- Mice
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Rad51 Recombinase -- metabolism
- Signal Transduction
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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