Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress. [electronic resource]
Producer: 20120113Description: 2013-20 p. digitalISSN:- 1873-3913
- AMP-Activated Protein Kinases -- metabolism
- Acetylcysteine -- pharmacology
- Animals
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Benzimidazoles -- pharmacology
- Calcium Signaling -- drug effects
- Calcium-Calmodulin-Dependent Protein Kinase Kinase -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Survival
- Chelating Agents -- pharmacology
- Egtazic Acid -- analogs & derivatives
- Endoplasmic Reticulum -- drug effects
- Enzyme Activation
- Female
- GTP-Binding Protein alpha Subunits, Gq-G11 -- metabolism
- Linoleic Acids, Conjugated -- pharmacology
- Lipid Peroxidation
- Mammary Neoplasms, Animal
- Mice
- Naphthalimides -- pharmacology
- Oxidants -- pharmacology
- Oxidative Stress
- Phosphorylation
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases -- metabolism
- Receptors, G-Protein-Coupled -- metabolism
- Signal Transduction
- Transcription Factor CHOP -- metabolism
- Type C Phospholipases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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