Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. [electronic resource]
Producer: 20110907Description: 1154-7 p. digitalISSN:- 1095-9203
- Carcinoma -- drug therapy
- Carcinoma, Squamous Cell
- Cell Cycle Proteins -- genetics
- Codon, Nonsense
- Exons
- F-Box Proteins -- genetics
- F-Box-WD Repeat-Containing Protein 7
- Gene Dosage
- Genes, Tumor Suppressor
- Genes, p53
- Head and Neck Neoplasms -- drug therapy
- Humans
- INDEL Mutation
- Mutation
- Mutation, Missense
- Neoplasms, Squamous Cell -- drug therapy
- Oligonucleotide Array Sequence Analysis
- Oncogenes
- Papillomaviridae -- isolation & purification
- Papillomavirus Infections -- virology
- Receptor, Notch1 -- chemistry
- Sequence Analysis, DNA
- Smoking
- Squamous Cell Carcinoma of Head and Neck
- Nicotiana
- Ubiquitin-Protein Ligases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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