The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins. [electronic resource]
Producer: 20120208Description: 4851-60 p. digitalISSN:- 1464-3391
- Alkanesulfonates -- chemical synthesis
- Antineoplastic Agents, Alkylating -- chemical synthesis
- Cell Hypoxia -- drug effects
- DNA -- chemistry
- Drug Design
- Drug Screening Assays, Antitumor
- Duocarmycins
- Female
- Humans
- Indoles -- chemistry
- Nitro Compounds -- chemical synthesis
- Prodrugs -- chemical synthesis
- Pyrrolidinones -- chemistry
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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