A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma. [electronic resource]
Producer: 20111003Description: 12461-6 p. digitalISSN:- 1091-6490
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Biphenyl Compounds -- pharmacology
- Cell Cycle
- Cell Line, Tumor
- Cell Survival
- Cyclin D1 -- antagonists & inhibitors
- Disease Models, Animal
- Gene Amplification
- Genes, bcl-2
- Humans
- Lymphoma, Mantle-Cell -- etiology
- Mice
- Nitrophenols -- pharmacology
- Piperazines -- pharmacology
- Sulfonamides -- pharmacology
- Xenograft Model Antitumor Assays
- bcl-2-Associated X Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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