Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits lipopolysaccharide-induced inflammatory response in macrophages via suppression of NF-κB, JNK and p38 MAPK pathways. [electronic resource]
Producer: 20120213Description: 851-9 p. digitalISSN:- 1420-908X
- Animals
- Cell Line
- Cyclooxygenase 2 -- genetics
- Humans
- I-kappa B Proteins -- metabolism
- Inflammation -- chemically induced
- Interleukin-1beta -- genetics
- Interleukin-6 -- genetics
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Lipopolysaccharides -- immunology
- Macrophages -- cytology
- Mice
- Mitogen-Activated Protein Kinases -- genetics
- Molecular Structure
- NF-KappaB Inhibitor alpha
- NF-kappa B -- genetics
- Naphthols -- chemistry
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Signal Transduction -- drug effects
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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