Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. [electronic resource]
Producer: 20110823Description: 663-71 p. digitalISSN:- 1529-2916
- Animals
- Antigens, Differentiation -- genetics
- Antigens, Viral -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Chronic Disease
- Lymphocyte Activation -- immunology
- Lymphocytic Choriomeningitis -- immunology
- Lymphocytic choriomeningitis virus -- immunology
- Mice
- Mice, Inbred C57BL
- Programmed Cell Death 1 Receptor
- T-Box Domain Proteins -- immunology
- Transcription, Genetic -- immunology
- T-bet Transcription Factor
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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