Assessment of the involvement of oxidative stress and Mitogen-Activated Protein Kinase signaling pathways in the cytotoxic effects of arsenic trioxide and its combination with sulindac or its metabolites: sulindac sulfide and sulindac sulfone on human leukemic cell lines. [electronic resource]
Producer: 20120918Description: 1161-72 p. digitalISSN:- 1559-131X
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Arsenic Trioxide
- Arsenicals -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Drug Synergism
- Glutathione -- metabolism
- Humans
- Leukemia -- drug therapy
- Mitogen-Activated Protein Kinases -- metabolism
- Oxidative Stress -- drug effects
- Oxides -- administration & dosage
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Sulindac -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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