An extension of the single threshold design for monitoring efficacy and safety in phase II clinical trials. [electronic resource]
Producer: 20120202Description: 1648-64 p. digitalISSN:- 1097-0258
- Algorithms
- Antineoplastic Agents -- adverse effects
- Bayes Theorem
- Bias
- Child
- Clinical Trials, Phase II as Topic -- adverse effects
- Computer Simulation
- Drug-Related Side Effects and Adverse Reactions
- Epidemiologic Research Design
- Humans
- Interleukin-12 -- adverse effects
- Melanoma -- drug therapy
- Models, Statistical
- Neuroblastoma -- drug therapy
- Probability
- Safety -- statistics & numerical data
- Sample Size
- Treatment Outcome
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Publication Type: Journal Article
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