Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells. [electronic resource]
Producer: 20110825Description: e18330 p. digitalISSN:- 1932-6203
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- BH3 Interacting Domain Death Agonist Protein -- genetics
- Bcl-2-Like Protein 11
- Cell Line
- Cell Line, Tumor
- Chromatin Immunoprecipitation
- Electrophoretic Mobility Shift Assay
- Hedgehog Proteins -- genetics
- Humans
- Immunoblotting
- Inhibitor of Apoptosis Proteins -- genetics
- Kruppel-Like Transcription Factors -- genetics
- Membrane Proteins -- genetics
- Nuclear Proteins -- genetics
- Promoter Regions, Genetic -- genetics
- Proto-Oncogene Proteins -- genetics
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Transcription Factors -- genetics
- Veratrum Alkaloids -- pharmacology
- X-Linked Inhibitor of Apoptosis Protein -- genetics
- Zinc Finger Protein GLI1
- Zinc Finger Protein Gli2
- bcl-2 Homologous Antagonist-Killer Protein -- genetics
- bcl-2-Associated X Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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